On the afternoon of May 13th, with the successful conclusion of various schedules, the 2018 China Intestinal Congress officially came to an end. More than 100 experts and scholars presented the latest research progress in the fields of human microbiome, animal gut, integrated intestinal disease, and microbial transplantation for the audience, bringing a top-class academic feast in the field of gut. From the opening ceremony to the sub-venue, the venue was full, and even on the last afternoon of the two venues, people were still crowded and popular.
At the opening ceremony on the morning of May 12th, Prof. Gao Fu from the Chinese Center for Disease Control and Prevention; Prof. Fan Daiming from Xijing Hospital of Gastroenterology, Air Force Medical University; Prof. Yin Yulong from Institute of Subtropical Agriculture, Chinese Academy of Sciences; Prof. Wei Fuwen from Institute of Zoology, Chinese Academy of Sciences; Prof. Zhao Liping from Rutgers University and Shanghai Jiao Tong University; and Prof. Dusko from the French National Institute of Agricultural Research Professor Ehrlich and Professor Wu Kaichun of Xijing Gastroenterology Hospital of Air Force Medical University made the first presentation.
In the China Integrated Enterology Conference & China Flora Transplantation Conference, the authoritative clinical experts shared the new achievements in various intestinal and related diseases, carried out interpretation and discussion on some difficult cases of complex intestinal diseases, and some experts in basic fields also introduced the clinical application value of their research.
Fecal bacteria transplantation is the most visible "star" in the whole conference. Several doctors elaborated on the efficacy and mechanism of fecal bacteria transplantation in various digestive tract diseases (including radiation enteritis, irritable bowel syndrome, ulcerative colitis, fatty liver, etc.), and outside the digestive tract, several doctors also discussed the clinical application of fecal bacteria transplantation in the treatment of diabetes, autism, psoriasis. While affirming the efficacy of fecal bacteria transplantation in a variety of diseases, experts also cautioned that in some diseases, fecal bacteria transplantation is only effective at the initial stage of treatment, suggesting possible rejection, and donor selection is also very important. To this end, several speakers described various microecological treatment centers and fecal bacteria banks, laying the foundation for the safety and effectiveness of fecal bacteria transplantation by establishing strict donor screening and management mechanisms, drug level management of the operating environment, and long-term monitoring of the status of transplant recipients. From the perspective of intestinal ecosystem, other experts in basic research have provided new ideas for improving the effect of microecological therapy such as fecal bacteria transplantation. In addition to fecal bacteria transplantation, probiotics are also an important part of microecological therapy. Several scholars dedicated to the screening and function of probiotics presented the function and mechanism of some probiotic strains to improve health, as well as the research results in clinical applications including various intestinal diseases.
In addition to treatment, the value of intestinal flora in disease diagnosis has also been paid attention by many experts. Intestinal flora has been found to contribute to the non-invasive diagnosis of non-alcoholic fatty liver disease, and can be used to predict the efficacy of biologics in inflammatory bowel disease. It also has a key influence on the efficacy of anticancer drugs. In addition, the meeting also introduced the diagnosis and early screening of intestinal tumors, genetic factors regulation of intestinal flora and other related studies.
In the China Human Microbiome Conference, researchers from home and abroad conducted wonderful academic exchanges in various fields and disciplines. In terms of health and disease, several experts introduced the correlation and causal relationship between intestinal flora and colorectal cancer, liver disease, AIDS, obesity, diabetes, skin/oral/intestinal flora and autoimmune diseases, as well as the specific mechanisms of microflora involvement in the pathogenesis and progression of various diseases, and looked forward to the prospect of developing personalized diagnosis and treatment methods using intestinal/oral/skin microflora. In addition, several experts described the importance of microbiome research in areas such as combating malnutrition, combating antibiotic resistance, and understanding blood sugar regulation in obese people.
In their report, the authors share some of the new tools and methods their team has developed for studying gut flora. These include in vitro simulation of intestinal organids using intestinal stem cells, new techniques for imaging analysis of intestinal flora, host-microbial association analysis to study the pathogenesis of complex immune-related diseases, strategies for studying associations between flora and chronic diseases, and more.
At the same time, some researchers from enterprises also introduced their research, including the impact of reproductive tract microflora on premature birth and children's health, the establishment of a comprehensive database using the intestinal microflora of Chinese people, and various methods of microflora data analysis, demonstrating the successful cases of transforming basic research into the result industry.
At the China Animal Intestine Conference, many experts and scholars shared how to regulate the intestinal and rumen flora by changing diet structure, adding probiotics, fecal bacteria transplantation and other methods, so as to improve the growth and health status of pigs, broilers, dairy goats, tilapia and other animals, and promote the healthy development of offspring. It provides more theoretical and practical basis for promoting the development of breeding industry from the perspective of microflora.
In animal farming, the overuse of antibiotics is a serious problem, and animal-derived antibiotic resistance also poses a great threat to human health. The experts also described many measures to deal with it in the report. Firstly, through the establishment of a sound monitoring network and database, the animal antibiotic resistance can be timely and accurately monitored. In addition, the research on the mechanism of antibiotic resistance such as heterozygous plasmid lays a theoretical foundation for the fight against drug resistance. Finally, natural growth promoters such as plant functional components were used to replace antibiotic growth promoters, antibiotic "adjuvants" were developed, and special antibiotics for animals were developed to effectively reduce the use of animal antibiotics.
In addition to the breeding industry, animal protection is also a major concern in the field of animal gut research. The study of the giant panda's intestinal flora is key to providing better protection for the "national treasure" environment. In addition, animal models are also of great significance for human health research. The report describes the development of sterile pig models, which may be used in the future to evaluate the effectiveness of childhood vaccines and to customize human organs.
At the Protein & Cell Conference, 9 Protein & Cell article authors shared their insights on the relationship between bacteria and obesity, colorectal cancer, cardiovascular health, personalized medicine, the ethics of bacteria research, and strategies for fecal bacteria transplantation. This special issue by Protein & Cell editor-in-chief Rao Zihe academician, executive editor Dr. Zhang Xiaoxue strong support, and by the Chinese Academy of Sciences Beijing Institute of Biology Professor Zhao Fangqing, Chinese Academy of Sciences Institute of Microbiology Professor Wang Jun as guest editor, from a number of units at home and abroad with the full collaboration of a number of authors. A printed edition will be distributed during the conference, and paying attendees will be given access to a Chinese translation, which is one of the innovations of the China Gut Conference.
There are more than 2,500 participants from home and abroad, including those over 90 years old. Speeches on "Intestines · Dao" and "Business · Dao" were also held at the same time, and nearly 50 enterprises participated in the exhibition of innovative enterprises at the China Intestines Conference.
China Intestinal Conference is a large-scale interdisciplinary and cross-professional academic exchange platform jointly initiated and founded by Professor Zhang Invention of the Second Affiliated Hospital of Nanjing Medical University and Mr. LAN Canhui of Warm-hearted Biotechnology Research Institute on the basis of the four sessions of China Integrated Enterology Academic Conference. 2018 China Intestinal Congress, Professor Zhang Invention, Mr. Blue Canhui specially invited Air Force Military Medical University digestive disease hospital Professor Nie Yongzhan, Chinese Academy of Sciences Microbiology Institute Professor Zhu Baoli, Army Military Medical University Basic Medical school Professor Wei Hong, Chinese Academy of Sciences Beijing Institute of Life Sciences Professor Zhao Fangqing, Chinese Academy of Sciences Microbiology Institute Professor Wang Jun, "Protein & It was jointly organized by Dr. Zhang Xiaoxue and other professionals from Cell Magazine. The conference is funded by the Warm-Hearted Biotechnology Research Institute and supported by Minfu Social Welfare Foundation and G30 members.
The wonderful 2018 China Intestinal Congress has come to a successful conclusion. Let's look forward to the 2019 China Intestinal Congress, where more cross-cutting research in the field of gut will emerge.
