Wuhan P4 laboratory location from the network
China's first P4 laboratory has been put into operation
A few days ago, Wuhan National Biosafety (Level 4) Laboratory (hereinafter referred to as "Wuhan P4 Laboratory"), a major cooperation project between the Chinese Academy of Sciences and Wuhan Municipal People's Government, passed the qualification and on-site evaluation of laboratory activities of the National Health and Family Planning Commission, and China's first P4 laboratory was officially put into operation.
P4 Laboratory is a large facility dedicated to the research and utilization of severe infectious diseases. It is the only safe place where humans can conduct experiments on severe viruses such as Ebola and Marburg. Before Wuhan P4 laboratory was built, only France, Canada, Germany, Australia, the United States, the United Kingdom and other major developed countries in the world had such devices.
After the outbreak of SARS in 2003, China started the construction of P4 laboratory strategically. After more than 10 years of construction, Wuhan P4 laboratory was officially put into operation.
Researchers are practicing in the P4 laboratory (from the web)
The internal structure of P4 laboratory in Wuhan
Wuhan P4 laboratory is a suspended structure, divided into four floors. From the bottom up, the bottom floor is sewage treatment and life support system; The second level is the core laboratory; The third layer is the filter system; The top level is the air conditioning system. The P4 laboratory includes cell laboratory, animal laboratory, dissection room and bacteria and virus preservation room.
Entering the laboratory requires layers of disinfection, wearing a positive pressure isolation protective suit with a transparent inflatable cover on the head and a blue breathing belt connected at the bottom to ensure that researchers can breathe in the protective suit without any contact with outside air.
According to reports, Wuhan P4 laboratory all air will be discharged after two levels of high efficiency filter treatment, solid pollutants to autoclave treatment, liquid pollutants to be treated by sewage treatment equipment, to ensure the thorough killing of pathogens, to ensure that the pathogens in the laboratory will not leak.
The air filtration system of Wuhan P4 Laboratory was revealed
Ebola, SARS, Marburg, such a terrible virus, once released will cause unimaginable damage.
Screenshot of official website of Wuhan P4 Laboratory
The picture above is from the official website of Wuhan P4 Laboratory. The CamContain safety protection system appeared in the picture. Camfil Farr provided the complete air filtration system for P4 Laboratory in Wuhan and undertook the most difficult and successful air filtration process.
Global application cases make connections
As the first P4 biosafety laboratory in China, Wuhan Institute of Virology referred to a large number of foreign high-level biological design experience at the beginning of the project. Camfil farr began contact with Wuhan Institute of Virology in 2006. Camfil farr has provided air filtration systems for more than half of the world's senior biosafety laboratories. The experience in foreign laboratories and the contact contact have made Camfil farr an ideal choice for Wuhan Virology Institute.
Different from the general application environment, the research objects of P4 laboratory are virulent infectious viruses, which are easy to spread through the air, and the consequences once leaked are unimaginable. P4 Laboratory ventilation and filtration system needs to meet three requirements:
§ Efficient filtration of laboratory air,
§ Have a safe, accurate and repeatable field verification method to ensure that the filtration system is free from any leakage risk;
§ In order to ensure the safety of personnel, it is necessary to implement the contact-free safe replacement of filters in daily maintenance.
Therefore, safety and reliability become the test, is the top priority of air filtration scheme.
The first "top send top row" scheme in China
Camfil farr designed the first air filtration scheme in China based on the rigorous operational requirements, which was used to replace the traditional design of "topfil farr" and ensured the purification effect and operational stability of the laboratory ventilation system.
In particular, the scheme uses CamContain, the world's leading safety protection filtration system, which has been recognized by many customers for its reliable filtration performance, advanced in situ disinfection, in situ scanning leak detection and comprehensive safety protection method.
CamContain safety protection filtration system
① Safety protection filter box ② in situ disinfection system ③ high efficiency filter section ④ differential pressure monitoring system ⑤ in situ scanning verification system
§ Efficient virus filtering
CamContain safety protection system is configured with HEPA high efficiency filter, 100% pass MPPS point-by-point scanning test, to ensure that all highly pathogenic microorganisms are effectively intercepted.
§ Safe, accurate, and repeatable field verification
CamContain has a top intelligent integrated scanning and verification system in the industry. After site installation, the efficiency of electric scanning will be verified, and the test results can be repeated to prevent the risk of leakage.
§ Contactless safety replacement
The in situ disinfection system configured in CamContain shall be verified for complete inactivation to ensure that the surface pathogenic microorganisms can be effectively killed before the filter is replaced. In conjunction with the BIBO bag in-bag out safety replacement technology, to ensure that the CamContain system will be isolated from personnel throughout the process of filter replacement.
Wide range of application cases
CamContain system has been used in over 50% of biosafety laboratories worldwide. In the country, all P4 and the vast majority of P3 biosafety laboratories under construction will contain the CamContain system on a large scale. For example:
Kunming Institute of Medical Biology, Chinese Academy of Medical Sciences
Harbin Institute of Veterinary Medicine, Chinese Academy of Sciences
§ Beijing Institute of Microbiology, Chinese Academy of Sciences
§ P3 Laboratory, Fudan University
§ Anhui Center for Disease Control
§ Jilin Center for Disease Control
Zhejiang Provincial Center for Disease Control and Prevention
§ P3 Laboratory, Zhejiang University
Shenzhen Center for Disease Control and Prevention
